Fluorous Phase-Enhanced Fluorescent Sensitivity for Enantioselective Recognition of Lysine
Jiaqiao Yang, Le Jiang, Jun Tian, Shanshan Yu, Xiao‐Qi Yu, Lin Pu
Abstract
)-2,6-bis(1-hydroxyethyl)pyridine and 2-naphthol containing a highly fluorinated alkyl group, is found to show enantioselective and chemoselective fluorescent recognition of lysine in the fluorous phase. We discovered that the fluorous phase greatly enhances the fluorescent sensitivity and selectivity of the probe. Thus, the fluorous phase not only can allow the fluorescence measurement to be conducted away from common organic and aqueous media to minimize undesirable interference but also can provide a unique environment to greatly improve the selective fluorescent response.
Topics & Concepts
ChemistryFluorescenceEnantioselective synthesisLysinePyridineSelectivityAlkylPhase (matter)Combinatorial chemistryAqueous mediumSensitivity (control systems)Aqueous two-phase systemAqueous solutionPhotochemistryOrganic chemistryAmino acidCatalysisBiochemistryQuantum mechanicsPhysicsEngineeringElectronic engineeringMolecular Sensors and Ion DetectionLuminescence and Fluorescent MaterialsPorphyrin and Phthalocyanine Chemistry