Silica nanoparticles induces sperm granuloma formation and blood-epididymal barrier disruption via the p38 MAPK pathway in mice
Fanyu Meng, Huiyu Hao, Zhiyi Guo, Wenpeng Liu, Shumin Zhang, Wenxuan Tang, Wendong Ma, Xuan Shang
Topics & Concepts
p38 mitogen-activated protein kinasesEpididymisCell biologyDownregulation and upregulationReactive oxygen speciesOxidative stressSpermEndocytosisChemistrySuperoxide dismutaseMAPK/ERK pathwayAndrologyMalondialdehydeSignal transductionBiologyBiochemistryMedicineGeneCellSperm and Testicular FunctionSelenium in Biological SystemsReproductive System and Pregnancy