Litcius/Paper detail

Exercise-induced regulation of adipose tissue

Andrew M. Stroh, Kristin I. Stanford

2023Current Opinion in Genetics & Development29 citationsDOIOpen Access PDF

Abstract

Exercise induces various beneficial whole-body adaptations and can delay the onset of obesity, type 2 diabetes, and cardiovascular disease. While many of the beneficial effects of exercise on skeletal muscle and the cardiovascular system have been well established, recent studies have highlighted the role of exercise-induced improvements to adipose tissue that affect metabolic and whole-body health. Studies investigating exercise-induced adaptations of white adipose tissue (WAT) and brown adipose tissue (BAT) demonstrate modifications to glucose uptake, mitochondrial activity, and endocrine profile, and a beiging of WAT in rodents. This review discusses recent studies of the exercise-induced adaptations to WAT and BAT and their implications.

Topics & Concepts

White adipose tissueAdipose tissueBrown adipose tissueBiologyEndocrinologyInternal medicineType 2 diabetesSkeletal muscleObesityEndocrine systemDiabetes mellitusHormoneMedicineAdipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity