Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex
Emma Gerrits, Lucia Giannini, Nieske Brouwer, Shamiram Melhem, Danielle Seilhean, Isabelle Le Ber, The Brainbank Neuro-CEB Neuropathology Network, Alwin Kamermans, Gijs Kooij, Helga E. de Vries, Erik Boddeke, Harro Seelaar, John C. van Swieten, Bart J. L. Eggen
Topics & Concepts
Frontotemporal dementiaNeuroscienceThalamusNeurovascular bundleCerebral cortexBiologyNucleusNeurodegenerationPsychologyDementiaMedicineAnatomyPathologyDiseaseNeuroinflammation and Neurodegeneration MechanismsRNA regulation and diseaseMitochondrial Function and Pathology