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Research Advance on Qingfei Paidu Decoction in Prescription Principle, Mechanism Analysis and Clinical Application

Wei Ren, Yue Ma, Raoqiong Wang, Pan Liang, Qin Sun, Qingrong Pu, Li Dong, Maryam Mazhar, Gang Luo, Sijin Yang

2021Frontiers in Pharmacology39 citationsDOIOpen Access PDF

Abstract

Since the sudden epidemic of coronavirus disease 2019 (COVID-19), the State Administration of Traditional Chinese Medicine immediately organized experts to formulate and screen the effective prescriptions of traditional Chinese medicine according to the characteristics of the novel coronavirus infection. Qingfei Paidu decoction (QFPDD) has been proven to be effective in multi-provincial clinical trials, and has been selected as a general prescription for the treatment of COVID-19 in different stages that was later promoted to be used nationwide. This review highlights the latest advances of QFPDD, focusing on the TCM theory, mechanism analysis, clinical application of QFPDD and its future perspectives. Moreover, an in-depth discussion of some valuable issues and possible development for future research on QFPDD is also discussed, aiming to provide a novel guide to combat the global epidemic COVID-19.

Topics & Concepts

Medical prescriptionMedicineTraditional Chinese medicineDecoctionAlternative medicineMechanism (biology)Traditional medicineCoronavirus disease 2019 (COVID-19)Intensive care medicineClinical trialCoronavirusDiseasePharmacologyInfectious disease (medical specialty)Internal medicinePathologyEpistemologyPhilosophyPharmacological Effects of Natural CompoundsPlant-based Medicinal ResearchTraditional Chinese Medicine Studies