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Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

Yangfei Xiang, Yoshiaki Tanaka, Benjamin Patterson, Sungmin Hwang, Eriona Hysolli, Bilal Çakır, Kun‐Yong Kim, Wanshan Wang, Young‐Jin Kang, Ethan M. Clement, Mei Zhong, Sang-Hun Lee, Yee Sook Cho, Prabir Patra, Gareth J. Sullivan, Sherman M. Weissman, In‐Hyun Park

2020Molecular Cell90 citationsDOIOpen Access PDF

Topics & Concepts

BiologyMECP2MutantFunction (biology)MutationCell biologyRett syndromeNeuroscienceGeneticsLoss functionPhenotypeGeneGenetics and Neurodevelopmental DisordersProtein Degradation and InhibitorsChromatin Remodeling and Cancer
Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons | Litcius