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Oral health in patients with end‐stage renal disease: A scoping review

Alexa M. G. A. Laheij, W. Rooijers, Lela Bidar, Lema Haidari, Aegida Neradová, Ralph de Vries, Frederik R. Rozema

2021Clinical and Experimental Dental Research25 citationsDOIOpen Access PDF

Abstract

OBJECTIVES: In patients with end stage, renal disease a high rate of morbidity and mortality is present. Studies suggest that end stage renal disease may affect oral health. Therefore, the aim of this study was to perform a scoping review on periodontal disease, dental caries, xerostomia, and hyposalivation in end stage renal disease patients. MATERIALS AND METHODS: A literature search (in PubMed and Embase.com) was performed up to September 29, 2020, in collaboration with a medical information specialist. Included outcome variables were the community periodontal index, probing pocket depth, gingival index, bleeding on probing, decayed-missing-filled-teeth, carious-absent-obturated index, Xerostomia Inventory and the (un)stimulated whole salivary flow rate. RESULTS: Forty three out of 1293 studies were included in the final review comprising 7757 end stage renal disease patients. The average age was 58.3 ± 29.4 years. 28.2%-78.8% of patients reported xerostomia and the (un)stimulated salivary flow rates were significantly lower. Higher community periodontal index scores were measured in end stage renal disease patients. More decayed-missing-filled-teeth were recorded, but no differences were found between groups. CONCLUSIONS: Xerostomia and hyposalivation were highly prevalent in end stage renal disease patients. Patients have more deepened pockets, but an equal number of carious teeth compared to healthy controls.

Topics & Concepts

MedicineEnd stage renal diseaseDentistryStage (stratigraphy)DiseasePeriodontitisOral healthPeriodontal diseaseKidney diseaseInternal medicineBiologyPaleontologyOral microbiology and periodontitis researchSalivary Gland Disorders and FunctionsOral and gingival health research