Initiation of PI3K/AKT pathway by IGF-1 decreases spinal cord injury-induced endothelial apoptosis and microvascular damage
Haibo Li, Renyi Kong, Bowen Wan, Lei Yang, Sheng Zhang, Xiaojian Cao, Hongtao Chen
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BSpinal cord injuryApoptosisMedicineTransfectionEndothelial stem cellCancer researchImmunologyCell biologyChemistrySpinal cordBiologyIn vitroCell cultureBiochemistryPsychiatryGeneticsSpinal Cord Injury ResearchBarrier Structure and Function StudiesNerve injury and regeneration