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A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

Iain Templeman, Harry Smith, Enhad A. Chowdhury, Yung-Chih Chen, Harriet A. Carroll, Drusus Johnson-Bonson, Aaron Hengist, Rowan Smith, Jade Creighton, David J. Clayton, Ian Varley, Leonidas G. Karagounis, Andrew Wilhelmsen, Kostas Tsintzas, Sue Reeves, Jean‐Philippe Walhin, Javier T. Gonzalez, Dylan Thompson, James A. Betts

2021Science Translational Medicine113 citationsDOIOpen Access PDF

Abstract

> 0.05). Alternate-day fasting less effectively reduces body fat mass than a matched degree of daily energy restriction and without evidence of fasting-specific effects on metabolic regulation or cardiovascular health.

Topics & Concepts

Intermittent fastingWeight lossRandomized controlled trialMedicineCalorie restrictionBody weightEnergy metabolismPhysiologyEnvironmental healthInternal medicineObesityDietary Effects on HealthDiet and metabolism studiesRegulation of Appetite and Obesity
A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults | Litcius