Antimicrobial peptide GL13K immobilized onto SLA-treated titanium by silanization: antibacterial effect against methicillin-resistant <i>Staphylococcus aureus</i> (MRSA)
Yusang Li, Ruiying Chen, Fushi Wang, Xinjie Cai, Yining Wang
Abstract
. Meanwhile, Cell Counting Kit 8 analysis and examination of cell morphology demonstrated that the SLA-GL13K coating had good cytocompatibility at antibacterial concentrations. Overall, all these results suggest that SLA-GL13K coating can be successfully fabricated using silanization, and is a promising candidate for controlling MRSA-induced implant-related infection.
Topics & Concepts
SilanizationStaphylococcus aureusAntimicrobialCoatingMethicillin-resistant Staphylococcus aureusMicrobiologyAntibioticsMaterials scienceBacteriaNanotechnologyBiologyGeneticsComposite materialAntimicrobial Peptides and ActivitiesAntimicrobial agents and applicationsPeptidase Inhibition and Analysis