Super-resolution localization microscopy: Toward high throughput, high quality, and low cost
Hongqiang Ma, Yang Liu
Abstract
After nearly 15 years since its initial debut, super-resolution localization microscopy that surpasses the diffraction-limited resolution barrier of optical microscopy has rapidly gotten out of the ivory tower and entered a new phase to address various challenging biomedical questions. Recent advances in this technology greatly increased the imaging throughput, improved the imaging quality, simplified the sample preparation, and reduced the system cost, making this technology suitable for routine biomedical research. We will provide our perspective on the recent technical advances and their implications in serving the community of biomedical research.
Topics & Concepts
ThroughputMicroscopyHigh resolutionPerspective (graphical)Computer scienceNanotechnologyResolution (logic)Materials scienceArtificial intelligenceOpticsTelecommunicationsPhysicsRemote sensingGeographyWirelessAdvanced Fluorescence Microscopy TechniquesNear-Field Optical MicroscopyAdvanced Electron Microscopy Techniques and Applications