Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane
Tingting Fan, Weikai Guo, Ting Shao, Wenbo Zhou, Pan Hu, Mingyao Liu, Yihua Chen, Zhengfang Yi
Topics & Concepts
ChemistryAntibioticsIn vivoBacteriaBacterial cell structureIn vitroAntibacterial activityAntibiotic resistanceAntibacterial agentMembraneCombinatorial chemistryMicrobiologyBiochemistryBiologyBiotechnologyGeneticsPhenothiazines and Benzothiazines Synthesis and ActivitiesAntimicrobial Peptides and ActivitiesSynthesis and biological activity