Pharmacological postconditioning with sappanone A ameliorates myocardial ischemia reperfusion injury and mitochondrial dysfunction via AMPK-mediated mitochondrial quality control
Xiaojing Shi, Yang Li, Yaguang Wang, Tiejia Ding, Xiaowen Zhang, Nan Wu
Topics & Concepts
MitophagyCardioprotectionMitochondrial biogenesisMitochondrial fissionAMPKMitochondrial permeability transition poreTFAMNRF1Reperfusion injuryPINK1MitochondrionPharmacologymitochondrial fusionChemistryCell biologyProtein kinase ABiologyMitochondrial DNAIschemiaMedicineInternal medicineBiochemistryKinaseApoptosisProgrammed cell deathAutophagyGeneCardiac Ischemia and ReperfusionCardiovascular Function and Risk FactorsMitochondrial Function and Pathology