Meddling with Metal Sensors: Fur-Family Proteins as Signaling Hubs
Caroline H. Steingard, John D. Helmann
Abstract
The ferric uptake regulator (Fur) protein is the founding member of the FUR superfamily of metalloregulatory proteins that control metal homeostasis in bacteria. FUR proteins regulate metal homeostasis in response to the binding of iron (Fur), zinc (Zur), manganese (Mur), or nickel (Nur).
Topics & Concepts
BiologySUPERFAMILYRegulatorZincIron homeostasisHomeostasisFerricProtein familyBacteriaMetalCell biologyBiochemistryGeneticsGeneChemistryOrganic chemistryTrace Elements in HealthChromium effects and bioremediationHeavy metals in environment