<i>In silico</i> evaluation of potential breast cancer receptor antagonists from GC-MS and HPLC identified compounds in <i>Pleurotus ostreatus</i> extracts
Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi, Shalom Nwodo Chinedu
Abstract
: The identified compounds in the class of phenols and flavonoids were better lead molecules due to their ability to strongly bind to the proteins' receptors. These compounds showed promising drug-like properties; they could be safe and new leads for creating anticancer medicines.
Topics & Concepts
Pleurotus ostreatusIn silicoChemistryChromatographyHigh-performance liquid chromatographyBreast cancerPharmacologyCancerBiologyMedicineFood scienceBiochemistryInternal medicineMushroomGeneFungal Biology and ApplicationsMicrobial Natural Products and BiosynthesisCancer Treatment and Pharmacology