Lyophilization and nebulization of pulmonary surfactant-coated nanogels for siRNA inhalation therapy
Pieterjan Merckx, Joris Lammens, Gust Nuytten, Bram Bogaert, Roberta Guagliardo, Tania Maes, Chris Vervaet, Thomas De Beer, Stefaan C. De Smedt, Koen Raemdonck
Topics & Concepts
RNA interferenceSmall interfering RNAGene knockdownNanocapsulesGene silencingChemistryNanogelIntracellularPulmonary surfactantBiophysicsRNACell biologyNanotechnologyNanoparticleMaterials scienceBiologyDrug deliveryBiochemistryApoptosisGeneRNA Interference and Gene DeliveryNeonatal Respiratory Health ResearchInhalation and Respiratory Drug Delivery