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Purification and Characterization of the Isoprene Monooxygenase from <i>Rhodococcus</i> sp. Strain AD45

Leanne P. Sims, Colin W. J. Lockwood, Andrew T. Crombie, Justin M. Bradley, Nick E. Le Brun, J. Colin Murrell

2022Applied and Environmental Microbiology11 citationsDOIOpen Access PDF

Abstract

Isoprene is a highly abundant climate-active gas and a carbon source for some bacteria. Analyses of the genes encoding isoprene monooxygenase (IsoMO) indicate this enzyme is a soluble diiron center monooxygenase in the same family of oxygenases as soluble methane monooxygenase, alkene monooxygenase, and toluene monooxygenase.

Topics & Concepts

IsoprenePseudomonas putidaMonooxygenaseBiochemistryRhodococcusMethane monooxygenaseOxygenaseChemistryBacteriaEscherichia coliDioxygenaseBiologyStereochemistryEnzymeOrganic chemistryGeneCytochrome P450GeneticsPolymerCopolymerMicrobial bioremediation and biosurfactantsMetal-Catalyzed Oxygenation MechanismsRadioactive element chemistry and processing
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