Exosomal thioredoxin-1 from hypoxic human umbilical cord mesenchymal stem cells inhibits ferroptosis in doxorubicin-induced cardiotoxicity via mTORC1 signaling
Yue Yu, Tianyu Wu, Yao Lu, Wei Zhao, Jiän Zhang, Qiushi Chen, Gaoyuan Ge, Yan Hua, Kaiyan Chen, Inam Ullah, Fengxiang Zhang
Topics & Concepts
CardiotoxicityGPX4ChemistryDoxorubicinMalondialdehydePharmacologyGlutathioneOxidative stressMesenchymal stem cellCancer researchCell biologyGlutathione peroxidaseBiochemistryMedicineSuperoxide dismutaseToxicityBiologyInternal medicineChemotherapyEnzymeOrganic chemistryFerroptosis and cancer prognosisExtracellular vesicles in diseasePeptidase Inhibition and Analysis