Discovery and optimization of 2,3-diaryl-1,3-thiazolidin-4-one-based derivatives as potent and selective cytotoxic agents with anti-inflammatory activity
Ahmed M. Shawky, Faisal A. Almalki, Ashraf N. Abdalla, Bahaa G. M. Youssif, Maha M. Abdel‐Fattah, Fatema Hersi, Hany A.M. El-Sherief, A. Ibrahim Nashwa, Ahmed M. Gouda
Topics & Concepts
ChemistryCytotoxicityCytotoxic T cellTubulinIC50MTT assayApoptosisIn vitroStereochemistryColchicineCancer cellMicrotubulePharmacologyBiochemistryCancerBiologyMedicineInternal medicineCell biologySynthesis and biological activitySynthesis and Biological Evaluation