Molecular editing of 3-hydroxyphenyl oxindole derivatives <i>via</i> formal O-insertion and N-insertion: synthesis of dioxolane spirooxindoles and quinoxalin-2(1 <i>H</i> )-ones
Yao‐Bin Shen, Jiawei Li, Peng Wang, Houchen Wang, Tiesheng Shi, Fangzhi Hu, Shuai‐Shuai Li
Abstract
Molecular editing of 3-hydroxyphenyl oxindole derivatives via formal O-insertion and N-insertion has been developed for synthesis of dioxolane spirooxindoles and quinoxalin-2(1 H )-ones.
Topics & Concepts
DioxolaneChemistryOxindoleCombinatorial chemistryStereochemistryTotal synthesisFormal synthesisMoleculeOrganic chemistryChemical synthesisSynthesis and Biological EvaluationChemical Synthesis and ReactionsChemical Synthesis and Analysis