Calcium-peroxide-mediated cascades of oxygen production and glutathione consumption induced efficient photodynamic and photothermal synergistic therapy
Lanfang Zhang, Hui Lü, Yu Tang, Xiaojie Lu, Zhendong Zhang, Yan Zhang, Ying Liu, Chenhui Wang
Abstract
The oxidative stress amplifier CaO 2 /ICG@ZIF-8 was constructed by loading CaO 2 and ICG onto ZIF-8, achieving efficient photodynamic and photothermal synergistic therapy by CaO 2 -mediated cascades of oxygen production and glutathione consumption.
Topics & Concepts
Photothermal therapyPhotodynamic therapyGlutathioneOxygenCalciumReactive oxygen speciesOxidative stressPeroxideChemistryMaterials sciencePhotothermal effectBiophysicsPhotochemistryNanotechnologyBiochemistryOrganic chemistryBiologyEnzymeNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisAdvanced Photocatalysis Techniques