New-onset pustular psoriasis in the setting of severe acute respiratory syndrome coronavirus 2 infection causing coronavirus disease 2019
Regine J. Mathieu, Caryn Cobb, Gladys H. Telang, Elnaz F. Firoz
Abstract
Psoriasis is a chronic, immune-mediated disorder mainly affecting the skin and joints. The pathogenesis involves keratinocyte hyperproliferation, complex cytokine and interleukin (IL) interactions, polygenic predisposition, and known association with environmental triggers, including infections, medications, trauma, and stress.1 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), is associated with not only flares of psoriasis in patients with well-documented disease2-4 but also other cutaneous diseases.
Topics & Concepts
MedicinePsoriasisCoronavirusPathogenesisImmunologyDiseaseCoronavirus disease 2019 (COVID-19)Immune systemDermatologyPathologyInfectious disease (medical specialty)Dermatological and COVID-19 studiesPsoriasis: Treatment and PathogenesisAutoimmune and Inflammatory Disorders Research