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Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

Elizabeth R. Gallagher, Peace T. Oloko, Tessa C. Fitch, Elizabeth M. Brown, Lynn A. Spruce, Erika L.F. Holzbaur

2024Current Biology12 citationsDOIOpen Access PDF

Topics & Concepts

BiologyHsp27Heat shock proteinPhosphorylationp38 mitogen-activated protein kinasesCell biologyCascadeShock (circulatory)MAPK/ERK pathwayHsp70BiochemistryInternal medicineGeneChromatographyChemistryMedicineAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27 | Litcius