New Cy5 photosensitizers for cancer phototherapy: a low singlet–triplet gap provides high quantum yield of singlet oxygen
He Ma, Saran Long, Jianfang Cao, Feng Xu, Panwang Zhou, Guang Zeng, Xiao Zhou, Chao Shi, Wen Sun, Jianjun Du, Keli Han, Jiangli Fan, Xiaojun Peng
Abstract
generation and good biocompatibility, causes an intense tumor ablation in mice. This provides a new strategy for designing ideal PSs for cancer photo-therapy.
Topics & Concepts
Singlet oxygenPhotosensitizerIntersystem crossingPhotochemistryQuantum yieldPhotodynamic therapyChemistryTriplet stateSinglet stateExcited stateOxygenMoleculeFluorescenceAtomic physicsOrganic chemistryPhysicsOpticsNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials