Establishing carbon–carbon double bond position and configuration in unsaturated fatty acids by gas-phase infrared spectroscopy
Carla Kirschbaum, Reuben S. E. Young, Kim Greis, Jan P. Menzel, Sandy Gewinner, Wieland Schöllkopf, Gerard Meijer, Gert von Helden, Tim Causon, Venkateswara R. Narreddula, Berwyck L. J. Poad, Stephen J. Blanksby, Kevin Pagel
Abstract
-octadecenoic acid in human-derived cell lines. Compatibility of 3-pyridylcarbinol ester derivatization with conventional chromatography-mass spectrometry and now gas-phase IR spectroscopy paves the way for comprehensive structure elucidation of fatty acids that is sensitive to regio- and stereochemical variations and with the potential to uncover new pathways in lipid metabolism.
Topics & Concepts
Infrared spectroscopyDouble bondCarbon fibersGas phaseChemistryInfraredSpectroscopyPhase (matter)Reinforced carbon–carbonPosition (finance)Organic chemistryPhotochemistryMaterials sciencePhysicsOpticsComposite materialEconomicsComposite numberQuantum mechanicsFinanceMass Spectrometry Techniques and ApplicationsAnalytical Chemistry and ChromatographyMolecular Spectroscopy and Structure