STS loaded PCL-MECM based hydrogel hybrid scaffolds promote meniscal regeneration <i>via</i> modulating macrophage phenotype polarization
Muzhe Li, Han Yin, Mingxue Chen, Haotian Deng, Guangzhao Tian, Weimin Guo, Guoliang Yi, Quanyi Guo, Zhiwei Chen, Shuyun Liu
Abstract
showed that hybrid scaffolds could induce M2 polarization in the early stage. In addition, the hybrid scaffolds seeded with MFCs could achieve good meniscus regeneration and chondroprotective effects in rabbits.
Topics & Concepts
Regeneration (biology)ScaffoldChemistryMeniscusMacrophage polarizationCell biologyMacrophageBiophysicsBiomedical engineeringIn vitroBiologyBiochemistryEngineeringIncidence (geometry)OpticsPhysicsKnee injuries and reconstruction techniquesTendon Structure and TreatmentOsteoarthritis Treatment and Mechanisms