Selective [3 + 2] Cycloaddition of Cyclopropenone Derivatives and Elemental Chalcogens
Jian Wu, Wenxia Gao, Xiaobo Huang, Yunbing Zhou, Miaochang Liu, Huayue Wu
Abstract
A highly efficient method is disclosed for the synthesis of 1,2-dichalcogen heterocycles via [3 + 2] cycloaddition of cyclopropenone derivatives and elemental chalcogens. Different from other cyclopropenone derivatives, cyclopropenselenones undergo unprecedented rearrangement with elemental sulfur. The features of this protocol include mild reaction conditions, high efficiency, excellent atom economy, gram-scale ability, and good regioselectivity.
Topics & Concepts
ChemistryCycloadditionRegioselectivityChalcogenSulfurAtom economyElemental analysisCombinatorial chemistryOrganic chemistryComputational chemistryCatalysisSulfur-Based Synthesis TechniquesSynthesis and Reactivity of Sulfur-Containing CompoundsClick Chemistry and Applications