Injectable hydrogels for bone regeneration with tunable degradability <i>via</i> peptide chirality modification
Weikai Chen, Shihao Sheng, Kai Tan, S. Wang, Xiang Wu, Yang Jiayi, Yan Hu, Liehu Cao, Ke Xu, Fengjin Zhou, Jiacan Su, Qin Zhang, Lei Yang
Abstract
, which in turn fosters bone regeneration by promoting cell migration and upregulating osteogenic gene expression. This research highlights the fundamental role of hydrogel degradability in bone repair and lays the groundwork for the advancement of degradable hydrogel technologies for bone regeneration, offering new insights and potential for future biomaterials development.
Topics & Concepts
Self-healing hydrogelsPolyethylene glycolChirality (physics)Regeneration (biology)PEG ratioDegradation (telecommunications)Materials sciencePeptideBiophysicsChemical engineeringChemistryPolymer chemistryBiochemistryCell biologyComputer scienceBiologyChiral symmetry breakingPhysicsQuantum mechanicsTelecommunicationsEngineeringNambu–Jona-Lasinio modelEconomicsFinanceQuarkBone Tissue Engineering MaterialsSupramolecular Self-Assembly in MaterialsConnective tissue disorders research