FOXP1 drives osteosarcoma development by repressing P21 and RB transcription downstream of P53
Hanjun Li, Xiuguo Han, Shengbing Yang, Yongjie Wang, Yang Dong, Tingting Tang
Topics & Concepts
OsteosarcomaCancer researchBiologyTranscription factorSmall hairpin RNAGene silencingMAPK/ERK pathwayCell growthGene knockdownSignal transductionCell biologyCell cultureGeneGeneticsinterferon and immune responsesSarcoma Diagnosis and TreatmentCancer-related Molecular Pathways