TNF-α-induced E3 ligase, TRIM15 inhibits TNF-α-regulated NF-κB pathway by promoting turnover of K63 linked ubiquitination of TAK1
Milton Roy, Kritarth Singh, Anjali Shinde, Jyoti Singh, Minal Mane, Sawani Bedekar, Yamini Tailor, Dhruv Gohel, Hitesh Vasiyani, Fatema Currim, Rajesh Singh
Topics & Concepts
UbiquitinUbiquitin ligaseNF-κBCell biologyProinflammatory cytokineSignal transductionNFKB1HEK 293 cellsCytosolTumor necrosis factor alphaBiologyChemistryGeneTranscription factorBiochemistryEnzymeInflammationEndocrinologyImmunologyNF-κB Signaling Pathwaysinterferon and immune responsesImmune Response and Inflammation