M2 macrophage-derived extracellular vesicles augment immune evasion and development of colorectal cancer via a circRNA_CCDC66/microRNA-342-3p/metadherin axis
Linfeng Fan, Guofeng Xu, Xiangfu Zeng
Topics & Concepts
Gene knockdownImmune systemmicroRNACancer researchMicrovesiclesDownregulation and upregulationMacrophageCD8BiologyColorectal cancerTumor microenvironmentChemistryCancerImmunologyCell cultureIn vitroBiochemistryGeneGeneticsCircular RNAs in diseasesMicroRNA in disease regulationMacrophage Migration Inhibitory Factor