Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity
Rosa Barreira da Silva, Ricardo Leitão, Ximo Pechuan-Jorge, Scott Werneke, Jason Oeh, Vincent Javinal, Yingyun Wang, Wilson Phung, Christine Everett, Jim Nonomiya, David Arnott, Cheng Lu, Yi-Chun Hsiao, James T. Koerber, Isidro Hötzel, James Ziai, Zora Modrušan, Thomas H. Pillow, Merone Roose‐Girma, Jill Schartner, Mark Merchant, Sascha Rutz, Céline Eidenschenk, Ira Mellman, Matthew L. Albert
Topics & Concepts
MonocyteCCL7ChemokineCancer researchMyeloidBiologyTumor microenvironmentInfiltration (HVAC)ImmunotherapyCell biologyCCL2Immune systemImmunologyThermodynamicsPhysicsImmune cells in cancerImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers