Purification of N-acetylgalactosamine-modified-oligonucleotides using orthogonal anion-exchange and mixed-mode chromatography approaches
Artaches A. Kazarian, Wesley W. Barnhart, Jason Long, Kelvin Sham, Bin Wu, Justin K. Murray
Topics & Concepts
ChemistryOligonucleotideChromatographySelectivityIon exchangeCombinatorial chemistryIonDNABiochemistryOrganic chemistryCatalysisRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid Chemistry