Difluorocarbene-enabled access to 1,3-oxazin-6-ones from enamides
Shuai Wang, Xin Li, Shengnan Jin, Kang Liu, Cong Dong, Jianke Su, Qiuling Song
Abstract
1,3-Oxazin-6-ones as important structural scaffolds widely exist in many bioactive or therapeutic agents.
Topics & Concepts
DifluorocarbeneChemistryMedicinal chemistryFluorine in Organic ChemistryCyclopropane Reaction MechanismsSynthesis and Reactions of Organic Compounds