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Nanosecond-Timescale Dynamics and Conformational Heterogeneity in Human GCK Regulation and Disease

Shawn M. Sternisha, A. Carl Whittington, Juliana A. Martinez Fiesco, Carol M. Porter, Malcolm M. McCray, Timothy M. Logan, Cristina Olivieri, Gianluigi Veglia, Peter Steinbach, Brian G. Miller

2020Biophysical Journal21 citationsDOIOpen Access PDF

Topics & Concepts

CooperativityAllosteric regulationNanosecondProtein dynamicsGlucokinaseChemistryBiophysicsPopulationMolecular dynamicsBiologyBiochemistryEnzymePhysicsComputational chemistryOpticsSociologyDemographyLaserHemoglobin structure and functionProtein Structure and DynamicsPancreatic function and diabetes
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