Objective response rate and progression-free survival as surrogates for overall survival treatment effect: A meta-analysis across diverse tumour groups and contemporary therapies
Adel Shahnam, Nadia Hitchen, Udit Nindra, Sathya Manoharan, Jayesh Desai, Ben Tran, Benjamin Solomon, Stephen J. Luen, Rina Hui, Ashley M. Hopkins, Michael J. Sorich
Topics & Concepts
MedicineInternal medicineSurrogate endpointRandomized controlled trialOncologyProgression-free survivalMalignancyOverall survivalMelanomaCancer researchStatistical Methods in Clinical TrialsMathematical Biology Tumor GrowthAdvanced Causal Inference Techniques