Biologically guided isolation and ADMET profile of new factor Xa inhibitors from<i>Glycyrrhiza glabra</i>roots using<i>in vitro</i>and<i>in silico</i>approaches
Reham S. Ibrahim, Rahma SR. Mahrous, Rasha M. Abu El-Khair, Samir A. Ross, Abdallah A. Omar, Hoda M. Fathy
Abstract
of 5.15 μM. The QikProp module was implemented to perform ADMET predictions for the screened compounds.
Topics & Concepts
IsoliquiritigeninChemistryChalconeIn vitroIsoflavonoidPharmacologyTraditional medicineStereochemistryFlavonoidBiochemistryAntioxidantBiologyMedicinePharmacological Effects of Natural CompoundsPlant-based Medicinal ResearchVitamin C and Antioxidants Research