In silico design and in vitro expression of novel multiepitope DNA constructs based on HIV-1 proteins and Hsp70 T-cell epitopes
Elahe Akbari, Kimia Kardani, Ali Namvar, Soheila Ajdary, Esmat Mirabzadeh, Vahid Khalaj, Azam Bolhassani
Topics & Concepts
EpitopeBiologyImmunogenicityVirologyCytotoxic T cellCTL*Major histocompatibility complexFusion proteinIn silicoT cellAntigenMolecular biologyRecombinant DNAImmune systemIn vitroGeneticsGenevaccines and immunoinformatics approachesHIV Research and TreatmentImmunotherapy and Immune Responses