Interaction energies between two antiandrogenic and one androgenic agonist receptor in the presence of a T877A mutation in prostate cancer: a quantum chemistry analysis
Katyanna Sales Bezerra, J. F. Vianna, José Xavier Neto, Jonas Ivan Nobre Oliveira, E.L. Albuquerque, Umberto L. Fulco
Abstract
We provide a detailed picture of the interactions between the androgen receptor T877A mutation and three different compounds used in the treatment of prostate cancer.
Topics & Concepts
ChemistryProstate cancerAgonistAndrogen receptorCancerCancer researchInternal medicineReceptorBiochemistryMedicineBiologyMass Spectrometry Techniques and ApplicationsAdvanced Chemical Physics StudiesHormonal and reproductive studies