Aptamers in cancer therapy: problems and new breakthroughs
Baijiang Jin, Zhukang Guo, Zhu Chen, Hui Chen, Song Li, Yan Deng, Lian Jin, Yuan Liu, Yuanying Zhang, Nongyue He
Abstract
is necessary. In this review, the obstructions mentioned above are thoroughly discussed and the methods to overcome these problems are introduced in detail. Furthermore, landmark research works and the most recent studies on aptamer-conjugated drugs for cancer therapy are also listed as examples, and the future directions of research for aptamer clinical transformation are discussed.
Topics & Concepts
AptamerNucleaseCancer therapyOligonucleotideNanotechnologyConjugated systemComputational biologyCancerComputer scienceMaterials scienceMedicineBiologyDNAMolecular biologyBiochemistryInternal medicineComposite materialPolymerAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryMolecular Junctions and Nanostructures