Litcius/Paper detail

Serial 68Ga-FAPI PET/CT After Treatment of Immunoglobulin G4-Related Pancreatitis and Retroperitoneal Fibrosis

Eunae Cho, Chang‐Hwan Park, Jahae Kim, Kangbin Kim, Sung Sun Kim

2023Clinical Nuclear Medicine12 citationsDOI

Abstract

ABSTRACT: Immunoglobulin G4 (IgG4)-related disease is a fibroinflammatory condition involving diverse organs. We report a case of IgG4-related pancreatitis and retroperitoneal fibrosis with serial 68Ga-FAPI PET/CT scans after treatment. A 64-year-old man presented with left flank and epigastric pain. Laboratory, abdominal CT, and 68Ga-FAPI PET/CT findings were suggestive of IgG4-related pancreatitis and retroperitoneal fibrosis. Histology of the pancreas confirmed IgG4-related pancreatitis. The follow-up PET/CT scans after treatment with steroid therapy showed regression of 68Ga-FAPI uptake in the pancreas and periureteral soft tissue. The changes on 68Ga-FAPI PET/CT scans were much more prominent compared with the CT scans.

Topics & Concepts

MedicinePancreatitisFibrosisPancreasRetroperitoneal fibrosisRadiologyPancreatic diseaseNuclear medicinePET-CTPathologyPositron emission tomographyInternal medicineIgG4-Related and Inflammatory DiseasesPeptidase Inhibition and AnalysisNeuroendocrine Tumor Research Advances