Fabrication, Evaluation, In Vivo Pharmacokinetic and Toxicological Analysis of pH-Sensitive Eudragit S-100-Coated Hydrogel Beads: a Promising Strategy for Colon Targeting
Sadia Rehman, Nazar Muhammad Ranjha, Hina Shoukat, Asadullah Madni, Faiz Ahmad, Muhammad Rafi Raza, Qazi Adnan Jameel, Abdul Majeed, Nasreen Ramzan
Topics & Concepts
Diclofenac SodiumSwellingPolyvinyl alcoholDrug deliveryChemistryEnteric coatingCoatingDiclofenacExtrusionSolubilityBeadChromatographyChemical engineeringPolymerMaterials scienceDosage formOrganic chemistryComposite materialEngineeringBiochemistryDrug Solubulity and Delivery SystemsHydrogels: synthesis, properties, applicationsGastrointestinal motility and disorders