Rosmarinic acid inhibits oxLDL-induced inflammasome activation under high-glucose conditions through downregulating the p38-FOXO1-TXNIP pathway
Jean Baptiste Nyandwi, Gyung Hyuck Ko, Hana Jin, Seung Pil Yun, Sang Won Park, Hye Jung Kim
Topics & Concepts
TXNIPThioredoxin-Interacting ProteinInflammasomeRosmarinic acidDownregulation and upregulationChemistryp38 mitogen-activated protein kinasesOxidative stressCell biologyAntioxidantBiochemistryProtein kinase AThioredoxinPhosphorylationBiologyReceptorGeneInflammasome and immune disordersAdipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity