Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain
Rafał Gulej, Ádám Nyúl‐Tóth, Chetan Ahire, Jordan DelFavero, Priya Balasubramanian, Tamás Kiss, Stefano Tarantini, Zoltán Benyó, Pál Pacher, Boglárka Csík, Andriy Yabluchanskiy, Péter Mukli, Anna Kuan‐Celarier, István A. Krizbai, Judith Campisi, William E. Sonntag, Anna Csiszár, Zoltán Ungvári
Topics & Concepts
Flow cytometryBlood–brain barrierMedicineCancer researchPathologyBiologyInternal medicineImmunologyCentral nervous systemNeuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomicsTelomeres, Telomerase, and Senescence