Design, synthesis and biological evaluation of novel thiazole-derivatives as mitochondrial targeting inhibitors of cancer cells
Xin Dang, Shuwen Lei, Shuhua Luo, Yixin Hu, Juntao Wang, Dongdong Zhang, Dan Lü, Faqin Jiang, Lei Fu
Topics & Concepts
HeLaThiazoleChemistryCancer cellMitochondrionCytotoxicityBiochemistryMTT assayCancerIn vitroCancer researchCombinatorial chemistryStereochemistryBiologyGeneticsATP Synthase and ATPases ResearchMitochondrial Function and PathologyCancer, Hypoxia, and Metabolism