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Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis

Placido Carlo Guidone, Roberta Seccia, Lelio Adelchi Fabrocini, Giuseppe Troiano, G Maffei, Maria Carmela Pedicillo, Giuseppe Pannone, Lorenzo Lo Muzio, Rosanna Zamparese, Giorgio Mori, Ilenia Sara De Stefano

2025Frontiers in Oral Health5 citationsDOIOpen Access PDF

Abstract

Congenital granular cell epulis (CGCE) is a rare benign tumor typically presenting at birth and most commonly located on the maxillary alveolar ridge. Case Presentation: We report the case of a five-day-old female with a smooth, multilobulated mass on the right maxillary alveolar ridge causing feeding difficulties. Surgical excision was performed under sedation. Histological and immunohistochemical analysis confirmed the diagnosis of CGCE. No recurrence was observed at one-month follow-up. Conclusion: Early diagnosis and surgical treatment of CGCE are essential to avoid functional impairment. The prognosis is excellent following complete excision.

Topics & Concepts

Alveolar ridgeEpulisMedicinePresentation (obstetrics)Surgical excisionCase presentationGranular cellSurgeryDentistryCentral nervous systemEndocrinologyImplantTumors and Oncological CasesTeratomas and Epidermoid CystsTracheal and airway disorders
Congenital granular cell epulis in a neonate: a case report and review of diagnosis, treatment, and prognosis | Litcius