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mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury

Long Shuang Huang, Zhigang Hong, Wei Wu, Shiqin Xiong, Ming Zhong, Xiaopei Gao, Jalees Rehman, Asrar B. Malik

2020Immunity426 citationsDOIOpen Access PDF

Topics & Concepts

Cell biologyBiologyCytosolSignal transductionEndothelial stem cellMitochondrionInflammationImmunologyBiochemistryIn vitroEnzymeInflammasome and immune disordersHippo pathway signaling and YAP/TAZinterferon and immune responses
mtDNA Activates cGAS Signaling and Suppresses the YAP-Mediated Endothelial Cell Proliferation Program to Promote Inflammatory Injury | Litcius