Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum
Jayesh Tandel, Katelyn A. Walzer, Jessica H. Byerly, Brittain Pinkston, Daniel P. Beiting, Boris Striepen
Abstract
The parasite Cryptosporidium infects millions of people worldwide each year, leading to life-threatening diarrheal disease in young children and immunosuppressed individuals. There is no vaccine and only limited treatment.
Topics & Concepts
BiologyCryptosporidium parvumGeneGeneticsTranscription factorParasitic Infections and DiagnosticsCoccidia and coccidiosis researchHelminth infection and control