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Synthetic lethality-mediated precision oncology via the tumor transcriptome

Joo Sang Lee, Nishanth Ulhas Nair, Gal Dinstag, Lesley M. Chapman, Youngmin Chung, Kun Wang, Sanju Sinha, Hongui Cha, Dasol Kim, Alexander Schperberg, Ajay Srinivasan, Vladimir Lazar, Eitan Rubin, Sohyun Hwang, Raanan Berger, Tuvik Beker, Ze’ev A. Ronai, Sridhar Hannenhalli, Mark R. Gilbert, Razelle Kurzrock, Se‐Hoon Lee, Kenneth Aldape, Eytan Ruppin

2021Cell159 citationsDOIOpen Access PDF

Topics & Concepts

BiologyTranscriptomePrecision oncologySynthetic lethalityLethalityComputational biologyPrecision medicineCancer researchGeneticsGeneGene expressionDNA repairCancer Genomics and DiagnosticsCancer Immunotherapy and BiomarkersLung Cancer Treatments and Mutations
Synthetic lethality-mediated precision oncology via the tumor transcriptome | Litcius