Synthetic lethality-mediated precision oncology via the tumor transcriptome
Joo Sang Lee, Nishanth Ulhas Nair, Gal Dinstag, Lesley M. Chapman, Youngmin Chung, Kun Wang, Sanju Sinha, Hongui Cha, Dasol Kim, Alexander Schperberg, Ajay Srinivasan, Vladimir Lazar, Eitan Rubin, Sohyun Hwang, Raanan Berger, Tuvik Beker, Ze’ev A. Ronai, Sridhar Hannenhalli, Mark R. Gilbert, Razelle Kurzrock, Se‐Hoon Lee, Kenneth Aldape, Eytan Ruppin
Topics & Concepts
BiologyTranscriptomePrecision oncologySynthetic lethalityLethalityComputational biologyPrecision medicineCancer researchGeneticsGeneGene expressionDNA repairCancer Genomics and DiagnosticsCancer Immunotherapy and BiomarkersLung Cancer Treatments and Mutations