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LncRNA Gaplinc promotes the pyroptosis of vascular endothelial cells through SP1 binding to enhance NLRP3 transcription in atherosclerosis

Yong Tang, Jianhua Yan, Zhuowang Ge, Aihua Fei, Yachen Zhang

2022Cellular Signalling28 citationsDOI

Topics & Concepts

PyroptosisInflammasomeCell biologyEndothelial stem cellPyrin domainDownregulation and upregulationBiologyEctopic expressionGene silencingTranscription factorCancer researchChemistryImmunologyInflammationGeneBiochemistryIn vitroInflammasome and immune disordersCancer-related molecular mechanisms researchinterferon and immune responses
LncRNA Gaplinc promotes the pyroptosis of vascular endothelial cells through SP1 binding to enhance NLRP3 transcription in atherosclerosis | Litcius